Transcriptomic Abnormalities in Epstein Barr Virus Associated T/NK Lymphoproliferative Disorders

by de Mel, Sanjay, Tan, Joshua Zhi-Chien, Jeyasekharan, Anand D, Chng, Wee-Joo, Ng, Siok-Bian
Published 2021

Molecular pathogenic pathways in extranodal NK/T cell lymphoma

by de Mel, Sanjay, Hue, Susan Swee-Shan, Jeyasekharan, Anand D, Chng, Wee-Joo, Ng, Siok-Bian
Published 2021

Quantitative Analysis of a Multiplexed Immunofluorescence Panel in T-Cell Lymphoma

by Ng, Siok-Bian, Fan, Shuangyi, Choo, Shoa-Nian, Hoppe, Michal, Phuong, Hoang Mai, De Mel, Sanjay, Jeyasekharan, Anand D
Published 2021

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

by Hong, Guo, Fan, Shuangyi, Phyu, The, Maheshwari, Priyanka, Hoppe, Michal Marek, Hoang, Mai Phuong, de Mel, Sanjay, Poon, Michelle, Ng, Siok-Bian, Jeyasekharan, Anand D
Published 2021

LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition

by Nagasawa, Satoi, Sedukhina, Anna S., Nakagawa, Yuko, Maeda, Ichiro, Kubota, Manabu, Ohnuma, Shigeko, Tsugawa, Koichiro, Ohta, Tomohiko, Roche-Molina, Marta, Bernal, Juan A., Narváez, Ana J., Jeyasekharan, Anand D, Sato, Ko
Published 2015

Sustained activation of non-canonical NF-κB signalling drives glycolytic reprogramming in doxorubicin-resistant DLBCL

by Lim, Shen Kiat, Peng, Chen Chen, Low, Shannon, Vijay, Varsheni, Budiman, Andrea, Phang, Beng Hooi, Lim, Jing Quan, Jeyasekharan, Anand D., Lim, Soon Thye, Ong, Choon Kiat, Tan, Suet Mien, Li, Yinghui
Published 2023

T and NK cell lymphoma cell lines do not rely on ZAP-70 for survival

by de Mel, Sanjay, Mustafa, Nurulhuda, Selvarajan, Viknesvaran, Azaman, Muhammad Irfan, Jaynes, Patrick William, Venguidessane, Shruthi, Phuong, Hoang Mai, Alnaseri, Zubaida Talal, Phyu, The, Girard, Louis-Pierre, Chng, Wee Joo, Wardyn, Joanna, Li, Ying, An, Omer, Yang, Henry, Ng, Siok Bian, Jeyasekharan, Anand D
Published 2022

Determinants of response to daratumumab in Epstein-Barr virus-positive natural killer and T-cell lymphoma

by Mustafa, Nurulhuda, Nee, Adina Huey Fang, Chooi, Jing Yuan, Toh, Sabrina Hui Min, Chung, Tae-Hoon, Selvarajan, Viknesvaran, Fan, Shuangyi, Ng, Siok Bian, Poon, Michelle, Chan, Esther, Lee, Joanne, Chee, Yen Lin, Jeyasekharan, Anand D, Zhou, Longen, Yang, Jennifer, Chng, Wee Joo
Published 2021

Real world experience of R-CHOP with or without consolidative radiotherapy vs DA-EPOCH-R in the first-line treatment of primary mediastinal B-cell lymphoma

by Li Chan, Esther Hian, Koh, Liang Piu, Lee, Joanne, De Mel, Sanjay, Jeyasekharan, Anand, Liu, Xin, Tang, Tiffany, Lim, Soon Thye, Tao, Miriam, Quek, Richard, Ras, Mohamad Farid Bin Harunal, Lee, Yuh Shan, Diong, Colin, Tan, Daryl, Kim, Seok Jin, Chee, Yen Lin, Poon, Li Mei Michelle
Published 2021

DNA damage signalling as an anti-cancer barrier in gastric intestinal metaplasia

by Krishnan, Vaidehi, Lim, Debbie Xiu En, Hoang, Phuong Mai, Srivastava, Supriya, Matsuo, Junichi, Huang, Kie Kyon, Zhu, Feng, Ho, Khek Yu, So, Jimmy Bok Yan, Khor, Christopher, Tsao, Stephen, Teh, Ming, Fock, Kwong Ming, Ang, Tiing Leong, Jeyasekharan, Anand D, Tan, Patrick, Yeoh, Khay-Guan, Ito, Yoshiaki
Published 2020

Epstein-Barr virus-associated primary nodal T/NK-cell lymphoma shows a distinct molecular signature and copy number changes

by Ng, Siok-Bian, Chung, Tae-Hoon, Kato, Seiichi, Nakamura, Shigeo, Takahashi, Emiko, Ko, Young-Hyeh, Khoury, Joseph D, Yin, C Cameron, Soong, Richie, Jeyasekharan, Anand D, Hoppe, Michal Marek, Selvarajan, Viknesvaran, Tan, Soo-Yong, Lim, Soon-Thye, Ong, Choon-Kiat, Nairismagi, Maarja-Liisa, Maheshwari, Priyanka, Choo, Shoa-Nian, Fan, Shuangyi, Lee, Chi-Kuen, Chuang, Shih-Sung, Chng, Wee-Joo
Published 2021

Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer

by Hoppe, Michal M, Jaynes, Patrick, Wardyn, Joanna D, Upadhyayula, Sai Srinivas, Tan, Tuan Zea, Lie, Stefanus, Lim, Diana GZ, Pang, Brendan NK, Lim, Sherlly, P S Yeong, Joe, Karnezis, Anthony, Chiu, Derek S, Leung, Samuel, Huntsman, David G, Sedukhina, Anna S, Sato, Ko, Topp, Monique D, Scott, Clare L, Choi, Hyungwon, Patel, Naina R, Brown, Robert, Kaye, Stan B, Pitt, Jason J, Tan, David SP, Jeyasekharan, Anand D
Published 2021

Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma

by Liu, Min, Bertolazzi, Giorgio, Sridhar, Shruti, Lee, Rui Xue, Jaynes, Patrick, Mulder, Kevin, Syn, Nicholas, Hoppe, Michal Marek, Fan, Shuangyi, Peng, Yanfen, Thng, Jocelyn, Chua, Reiya, Jayalakshmi, Batumalai, Yogeshini, De Mel, Sanjay, Poon, Limei, Chan, Esther Hian Li, Lee, Joanne, Hue, Susan Swee-Shan, Chang, Sheng-Tsung, Chuang, Shih-Sung, Chandy, Kanianthara George, Ye, Xiaofei, Pan-Hammarström, Qiang, Ginhoux, Florent, Chee, Yen Lin, Ng, Siok-Bian, Tripodo, Claudio, Jeyasekharan, Anand D.
Published 2024

A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway.

by Parikh, Bhav Harshad, Liu, Zengping, Blakeley, Paul, Lin, Qianyu, Singh, Malay, Ong, Jun Yi, Ho, Kim Han, Lai, Joel Weijia, Bogireddi, Hanumakumar, Tran, Kim Chi, Lim, Jason YC, Xue, Kun, Al-Mubaarak, Abdurrahmaan, Yang, Binxia, R, Sowmiya, Regha, Kakkad, Wong, Daniel Soo Lin, Tan, Queenie Shu Woon, Zhang, Zhongxing, Jeyasekharan, Anand D, Barathi, Veluchamy Amutha, Yu, Weimiao, Cheong, Kang Hao, Blenkinsop, Timothy A, Hunziker, Walter, Lingam, Gopal, Loh, Xian Jun, Su, Xinyi
Published 2022

Integration of antiangiogenic therapy with cisplatin and gemcitabine chemotherapy in patients with nasopharyngeal carcinoma.

by Chong, Wan Qin, Lim, Chwee Ming, Sinha, Arvind Kumar, Tan, Chee Seng, Chan, Gloria Hui Jia, Huang, Yiqing, Barr Kumarakulasinghe, Nesaretnam, Sundar, Raghav, Jeyasekharan, Anand D, Loh, Woei Shyang, Tay, Joshua K., Yadav, Kritika, Wang, Lingzhi, Wong, Andrea L., Kong, Li Ren, Soo, Ross Andrew, Lau, Jieying Amelia, Soon, Yu Yang, Goh, Robby Miguel, Ho, Francis Cho Hao, Chong, Siew Meng, Lee, Soo-Chin, Loh, Kwok Seng, Tai, Bee Choo, Lim, Yaw Chyn, Goh, Boon Cher
Published 2020

Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS.

by Wai, Cho Mar Myint, Chen, Shangying, Phyu, The, Fan, Shuangyi, Leong, Sai Mun, Zheng, Wenning, Low, Louis Ching Yi, Choo, Shoa-Nian, Lee, Chi-Kuen, Chung, Tae-Hoon, Ban, Kenneth Hon Kim, Ghosh, Soumita, Lie, Stefanus, Kato, Seiichi, Nakamura, Shigeo, Takahashi, Emiko, Ko, Young-Hyeh, Khoury, Joseph D, Chuang, Shih-Sung, Au-Yeung, Rex KH, Tan, Soo-Yong, Lim, Soon-Thye, Ong, Choon-Kiat, Ho, Yong-Howe, Poon, Li Mei, De Mel, Sanjay, Jeyasekharan, Anand D, Chng, Wee-Joo, Otto, Franziska, Quintanilla-Martinez, Leticia, Zanardi, Federica, Iannelli, Fabio, Tripodo, Claudio, Pitt, Jason J, Ng, Siok-Bian
Published 2022

Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition

by Sundar, Raghav, Huang, Kie-Kyon, Kumar, Vikrant, Ramnarayanan, Kalpana, Demircioglu, Deniz, Her, Zhisheng, Ong, Xuewen, Isa, Zul Fazreen Bin Adam, Xing, Manjie, Tan, Angie Lay-Keng, Tai, David Wai Meng, Choo, Su Pin, Zhai, Weiwei, Lim, Jia Qi, Das Thakur, Meghna, Molinero, Luciana, Cha, Edward, Fasso, Marcella, Niger, Monica, Pietrantonio, Filippo, Lee, Jeeyun, Jeyasekharan, Anand D, Qamra, Aditi, Patnala, Radhika, Fabritius, Arne, De Simone, Mark, Yeong, Joe, Ng, Cedric Chuan Young, Rha, Sun Young, Narita, Yukiya, Muro, Kei, Guo, Yu Amanda, Skanderup, Anders Jacobsen, So, Jimmy Bok Yan, Yong, Wei Peng, Chen, Qingfeng, Goke, Jonathan, Tan, Patrick
Published 2022

Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma

by Hoppe, Michal Marek, Jaynes, Patrick, Fan, Shuangyi, Peng, Yanfen, Sridhar, Shruti, Hoang, Phuong Mai, Liu, Clementine Xin, De Mel, Sanjay, Poon, Limei, Chan, Esther Hian Li, Lee, Joanne, Ong, Choon Kiat, Tang, Tiffany, Lim, Soon Thye, Nagarajan, Chandramouli, Grigoropoulos, Nicholas F, Tan, Soo-Yong, Hue, Susan Swee-Shan, Change, Sheng-Tsung, Chuange, Shih-Sung, Li, Shaoying, Khoury, Joseph D, Harris III, Carl, Bottos, Alessia, Gay, Laura J, Runge, Hendrik FP, Moutsopoulos, Ilias, Mohorianu, Irina, Hodson, Daniel J, Farinha, Pedro, Mottok, Anja, Scott, David W, Pitt, Jason J, Chen, Jinmiao, Kumar, Gayatri, Kannan, Kasthuri, Chug, Wee Joo, Chee, Yen Lin, Ng, Siok-Bia, Tripodoe, Claudio, Jeyasekharan, Anand D
Published 2023

A genomic-augmented multivariate prognostic model for the survival of Natural-killer/T-cell lymphoma patients from an international cohort.

by Lim, Jing Quan, Huang, Dachuan, Chan, Jason Yongsheng, Laurensia, Yurike, Wong, Esther Kam Yin, Cheah, Daryl Ming Zhe, Chia, Burton Kuan Hui, Chuang, Wen-Yu, Kuo, Ming-Chung, Su, Yi-Jiun, Cai, Qing-Qing, Feng, Yanfen, Rao, Huilan, Feng, Li-Na, Wei, Pan-Pan, Chen, Jie-Rong, Han, Bo-Wei, Lin, Guo-Wang, Cai, Jun, Fang, Yu, Tan, Jing, Hong, Huangming, Liu, Yanhui, Zhang, Fen, Li, Wenyu, Poon, Michelle LM, Ng, Siok-Bian, Jeyasekharan, Anand, Ha, Jeslin Chian Hung, Khoo, Lay Poh, Chin, Suk Teng, Pang, Wan Lu, Kee, Rebecca, Cheng, Chee Leong, Grigoropoulos, Nicholas Francis, Tang, Tiffany, Tao, Miriam, Farid, Mohamad, Puan, Kia Joo, Xiong, Jie, Zhao, Wei-Li, Khor, Chiea Chuen, Hwang, William, Kim, Won Seog, Campo, Elias, Tan, Patrick, Teh, Bin Tean, Chng, Wee-Joo, Rötzschke, Olaf, Tousseyn, Thomas, Huang, Hui-Qiang, Rozen, Steve, Lim, Soon Thye, Shih, Lee-Yung, Bei, Jin-Xin, Ong, Choon Kiat
Published 2022