Pathogenesis of cholangiocarcinoma: From genetics to signalling pathways

by Kongpetch, Sarinya, Jusakul, Apinya, Ong, Choonkiat, Lim, Weng Khong, Rozen, Steve G., Tan, Boon Ooi Patrick, Teh, Bin Tean
Published 2016

Inhibition of placental growth factor in renal cell carcinoma

by Bessho, Hideharu, Wong, Bernice, Huang Dan, Siew, Ee Yan, Huang, Dachuan, Tan, Jing, Ong, Choonkiat, Tan, Sooyong, Matsumoto, Kazumasa, Iwamura, Masatsugu, Teh, Bin Tean
Published 2016

Methylation Profiles Reveal Distinct Subgroup of Hepatocellular Carcinoma Patients with Poor Prognosis (vol 9, e104158, 2014)

by Mah, Way-Champ, Thurnherr, Thomas, Chow, Pierce KH, Chung, Alexander YF, Ooi, London LPJ, Toh, Han Chong, Teh, Bin Tean, Saunthararajah, Yogen, Lee, Caroline GL
Published 2022

Functional characterisation guides classification of novel BAP1 germline variants

by Hong, Jing Han, Chong, Siao Ting, Lee, Po-Hsien, Tan, Jing, Heng, Hong Lee, Nur Diana Ishak, Chan, Sock Hoai, Teh, Bin Tean, Ngeow, Joanne
Published 2021

Clinical implications of systemic and local immune responses in human angiosarcoma

by Chan, Jason Yongsheng, Tan, Grace Fangmin, Yeong, Joe, Ong, Chee Wee, Ng, Dave Yong Xiang, Lee, Elizabeth, Koh, Joanna, Ng, Cedric Chuan-Young, Lee, Jing Yi, Liu, Wei, Wong, Ru Xin, Ong, Chin-Ann Johnny, Farid, Mohamad, Teh, Bin Tean, Soo, Khee Chee
Published 2022

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational en...

by Yu Shun Shing, Willie, McPherson John Richard, Stevenson Mark, Van Eijk Ronald, Heng Hong Lee, Newey Paul, Gan Anna, Ruano Dina, Huang Dachuan, Poon Song Ling, Ong Choon Kiat, Van Wezel T, Cavaco B., Rozen Steven George, Tan Patrck, Teh Bin Tean, Thakker Rajesh V., Morreau Hans
Published 2016

Mutation signatures implicate aristolochic acid in bladder cancer development

by Poon, Song Ling, Huang, Mi Ni, Choo, Yang, McPherson, John R., Yu, Willie Shun Shing, Heng, Hong Lee, Gan, Anna, Myint, Swe, Siew, Ee Yan, Ler, Lian Dee, Ng, Guat L., Weng, Wen-Hui, Chuang, Chengkeng, Yuen, John S.P., Pang, Seetong, Tan, Patrick, Teh, Bin Tean, Rozen, Steven G.
Published 2016

Family history assessment significantly enhances delivery of precision medicine in the genomics era

by Bylstra, Yasmin, Lim, Weng Khong, Kam, Sylvia, Tham, Koei Wan, Wu, R. Ryanne, Teo, Jing Xian, Davila, Sonia, Kuan, Jyn Ling, Chan, Sock Hoai, Bertin, Nicolas, Yang, Cheng Xi, Rozen, Steve, Teh, Bin Tean, Yeo, Khung Keong, Cook, Stuart Alexander, Jamuar, Saumya Shekhar, Ginsburg, Geoffrey S., Orlando, Lori A., Tan, Patrick
Published 2022

Correction to: Family history assessment significantly enhances delivery of precision medicine in the genomics era (Genome Medicine, (2021), 13, 1, (3), 10.1186/s13073-020-00819-1)

by Bylstra, Yasmin, Lim, Weng Khong, Kam, Sylvia, Tham, Koei Wan, Wu, R. Ryanne, Teo, Jing Xian, Davila, Sonia, Kuan, Jyn Ling, Chan, Sock Hoai, Bertin, Nicolas, Yang, Cheng Xi, Rozen, Steve, Teh, Bin Tean, Yeo, Khung Keong, Cook, Stuart Alexander, Jamuar, Saumya Shekhar, Ginsburg, Geoffrey S., Orlando, Lori A., Tan, Patrick
Published 2022

Mutation signatures implicate aristolochic acid in bladder cancer development

by Poon, Song Ling, Huang, Mi Ni, Choo, Yang, McPherson, John R., Yu, Willie Shun Shing, Heng, Hong Lee, Gan, Anna, Myint, Swe, Siew, Ee Yan, Ler, Lian Dee, Ng, Lay Guat, Weng, Wen-Hui, Chuang, Cheng-Keng, Yuen, John S. P., Pang, See-Tong, Tan, Patrick, Teh, Bin Tean, Rozen, Steven G.
Published 2015

Germline mutations in cancer predisposition genes are frequent in sporadic sarcomas

by Chan, Sock Hoai, Lim, Weng Khong, Nur Diana Binte Ishak, Li, Shao-Tzu, Goh, Wei Lin, Tan, Gek San, Lim, Kiat Hon, Teo, Melissa, Ng, Cedric Chuan Young, Malik, Simeen, Tan, Mann Hong, Teh, Jonathan Yi Hui, Chin, Francis Kuok Choon, Kesavan, Sittampalam, Selvarajan, Sathiyamoorthy, Tan, Patrick, Teh, Bin Tean, Soo, Khee Chee, Mohamad Farid, Quek, Richard, Ngeow, Joanne
Published 2018

Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia

by Fukawa, Tomoya, Ong, Pauline, Li, Zhimei, Chen, Shuwen, Mak, Shi Ya, Kanayama, Hiro-omi, Mohan, Rosmin Elsa, Wang, Ruiqi Rachel, Chua, Benjamin Yan-Jiang, Chua, Jason Min-Wen, Tan, Elwin Jun-Hao, Huang, Dan, Qian, Chao-Nan, Lim, Wan Jun, Lai, Jiunn Herng, Chua, Clarinda, Ong, Hock Soo, Tan, Ker-Kan, Ho, Ying Swan, Tan, Iain Beehuat, Teh, Bin Tean, Ng, Shyh-Chang
Published 2017

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development

by Chia, Na-Yu, Deng, Niantao, Kakoli, Das, Huang, Dachuan, Hu, Longyu, Zhu, Yansong, Lim, Kiat Hon, Lee, Ming-Hui, Wu, Jeanie, Sam, Xin Xiu, Tan, Gek San, Wan, Wei Keat, Yu, Willie, Gan, Anna, Tan, Lay Keng Angie, Tay, Su-Ting, Soo, Khee Chee, Wong, Wai Keong, Dominguez, Lourdes Trinidad, Ng, Huck-Hui, Rozen, Steven George, Goh, Liang Kee, Teh, Bin Tean, Tan, Boon Ooi Patrick
Published 2016

Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development

by Chia, Na Yu, DENG NIANTAO, Das, Kakoli, Huang, Dachuan, Hu, Longyu, Zhu, Yansong, Lim, Kiat Hon, Lee, Ming-Hui, Wu, Jeanie, Sam, Xin Xiu, Tan, Gek San, Wan, Wei Keat, Yu, Willie, Gan, Anna, Tan, Lay Keng Angie, Tay, Su Ting, Soo, Khee Chee, Wong, Wai Keong, Dominguez, Lourdes Trinidad M., Ng, Huck Hui, Rozen, Steven George, Goh, Liang Kee, Teh, Bin Tean, Tan, Boon Ooi Patrick
Published 2015

Oncogenic activation of the stat3 pathway drives pd-l1 expression in natural killer/t-cell lymphoma

by Song, Tammy Linlin, Nairismägi, Maarja-Liisa, Laurensia, Yurike, Lim, Jing-Quan, Tan, Jing, Li, Zhi-Mei, Pang, Wan-Lu, Kizhakeyil, Atish, Wijaya, Giovani-Claresta, Huang, Da-Chuan, Nagarajan, Sanjanaa, Chia, Burton Kuan-Hui, Cheah, Daryl, Liu, Yan-Hui, Zhang, Fen, Rao, Hui-Lan, Tang, Tiffany, Wong, Esther Kam-Yin, Bei, Jin-Xin, Iqbal, Jabed, Grigoropoulos, Nicholas-Francis, Ng, Siok-Bian, Chng, Wee-Joo, Teh, Bin-Tean, Tan, Soo-Yong, Verma, Navin Kumar, Fan, Hao, Lim, Soon-Thye, Ong, Choon-Kiat
Published 2019

Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma

by Song, Tammy Linlin, Nairismagi, Maarja-Liisa, Laurensia, Yurike, Lim, Jing-Quan, Tan, Jing, Li, Zhi-Mei, Pang, Wan-Lu, Kizhakeyil, Atish, Wijaya, Giovani-Claresta, Huang, Da-Chuan, Nagarajan, Sanjanaa, Chia, Burton Kuan-Hui, Cheah, Daryl, Liu, Yan-Hui, Zhang, Fen, Rao, Hui-Lan, Tang, Tiffany, Wong, Esther Kam-Yin, Bei, Jin-Xin, Iqbal, Jabed, Grigoropoulos, Nicholas-Francis, Ng, Siok-Bian, Chng, Wee-Joo, Teh, Bin-Tean, Tan, Soo-Yong, Verma, Navin Kumar, Fan, Hao, Lim, Soon-Thye, Ong, Choon-Kiat
Published 2021

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study

by Li, Zheng, Xia, Yi, Feng, Li-Na, Chen, Jie-Rong, Li, Hong-Min, Cui, Jing, Cai, Qing-Qing, Sim, Kar Seng, Nairismagi, Maarja-Liisa, Laurensia, Yurike, Meah, Wee Yang, Liu, Wen-Sheng, Guo, Yun-Miao, Chen, Li-Zhen, Feng, Qi-Sheng, Pang, Chi Pui, Chen, Li Jia, Chew, Soo Hong, Ebstein, Richard P, Foo, Jia Nee, Liu, Jianjun, Ha, Jeslin, Khoo, Lay Poh, Chin, Suk Teng, Zeng, Yi-Xin, Aung, Tin, Chowbay, Balram, Diong, Colin Phipps, Zhang, Fen, Liu, Yan-Hui, Tang, Tiffany, Tao, Miriam, Quek, Richard, Mohamad, Farid, Tan, Soo Yong, Teh, Bin Tean, Ng, Siok Bian, Chng, Wee Joo, Ong, Choon Kiat, Okada, Yukinori, Raychaudhuri, Soumya, Lim, Soon Thye, Tan, Wen, Peng, Rou-Jun, Khor, Chiea Chuen, Bei, Jin-Xin
Published 2021

A genomic-augmented multivariate prognostic model for the survival of Natural-killer/T-cell lymphoma patients from an international cohort.

by Lim, Jing Quan, Huang, Dachuan, Chan, Jason Yongsheng, Laurensia, Yurike, Wong, Esther Kam Yin, Cheah, Daryl Ming Zhe, Chia, Burton Kuan Hui, Chuang, Wen-Yu, Kuo, Ming-Chung, Su, Yi-Jiun, Cai, Qing-Qing, Feng, Yanfen, Rao, Huilan, Feng, Li-Na, Wei, Pan-Pan, Chen, Jie-Rong, Han, Bo-Wei, Lin, Guo-Wang, Cai, Jun, Fang, Yu, Tan, Jing, Hong, Huangming, Liu, Yanhui, Zhang, Fen, Li, Wenyu, Poon, Michelle LM, Ng, Siok-Bian, Jeyasekharan, Anand, Ha, Jeslin Chian Hung, Khoo, Lay Poh, Chin, Suk Teng, Pang, Wan Lu, Kee, Rebecca, Cheng, Chee Leong, Grigoropoulos, Nicholas Francis, Tang, Tiffany, Tao, Miriam, Farid, Mohamad, Puan, Kia Joo, Xiong, Jie, Zhao, Wei-Li, Khor, Chiea Chuen, Hwang, William, Kim, Won Seog, Campo, Elias, Tan, Patrick, Teh, Bin Tean, Chng, Wee-Joo, Rötzschke, Olaf, Tousseyn, Thomas, Huang, Hui-Qiang, Rozen, Steve, Lim, Soon Thye, Shih, Lee-Yung, Bei, Jin-Xin, Ong, Choon Kiat
Published 2022