Themis-associated phosphatase activity controls signaling in T cell development

by Mehta, Monika, Brzostek, Joanna, Chen, Elijah W, Tung, Desmond WH, Chen, Shuting, Sankaran, Shvetha, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas RJ
Published 2023

Lck bound to coreceptor is less active than free Lck

by Wei, Qianru, Brzostek, Joanna, Sankaran, Shvetha, Casas, Javier, Hew, Lois Shi-Qi, Yap, Jiawei, Zhao, Xiang, Wojciech, Lukasz, Gascoigne, Nicholas RJ
Published 2023

Targeting car to the peptide?mhc complex reveals distinct signaling compared to that of tcr in a jurkat t cell model

by Wu, Ling, Brzostek, Joanna, Sankaran, Shvetha, Wei, Qianru, Yap, Jiawei, Tan, Triscilla Y. Y., Lai, Junyun, Macary, Paul A., Gascoigne, Nicholas R. J.
Published 2022

Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing V?3.2 TCR in Themis-Deficient Mice

by Prasad, Mukul, Wojciech, Lukasz, Brzostek, Joanna, Hu, Jianfang, Chua, Yen Leong, Tung, Desmond Wai Hon, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Published 2022

Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides

by Choo, Joanna A. L., Thong, Sock Yue, Yap, Jiawei, van Esch, Wim J. E., Raida, Manfred, Meijers, Rob, Lescar, Julien, Verhelst, Steven H. L., Grotenbreg, Gijsbert M.
Published 2015

Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry

by Ser, Zheng, Gu, Yue, Yap, Jiawei, Lim, Yan Ting, Wang, Shi Mei, Hamidinia, Maryam, Murali, Tanusya Murali, Kumar, Ragini, Gascoigne, Nicholas RJ, Macary, Paul A, Sobota, Radoslaw M
Published 2024

Utilizing distinct CAR and TCR signaling to generate enhanced cellular immunotherapy

by Gascoigne, Nicholas RJ, Wu, Ling, Brzostek, Joanna, Wei, Qianru, Vale, Previtha Dawn Sakthi, Koh, Clara KT, Chua, Yen Long, Yap, Jiawei, Tan, Triscilla YY, Lai, Junyun, MacAry, Paul A
Published 2023

CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

by Wu, Ling, Brzostek, Joanna, Vale, Previtha Dawn Sakthi, Wei, Qianru, Koh, Clara KT, Ong, June Xu Hui, Wu, Liang-zhe, Tan, Jia Chi, Chua, Yen Leong, Yap, Jiawei, Song, Yuan, Tan, Vivian Jia Yi, Tan, Triscilla YY, Lai, Junyun, MacAry, Paul A, Gascoigne, Nicholas RJ
Published 2023

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A(star)11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad EZ, Murali, Tanusya M, Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline TH, Teo, Rachel ZC, Wood, Kathryn J, Hanson, Brendon J, Gascoigne, Nicholas RJ, Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A
Published 2021

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Published 2019