HASE: Framework for efficient high-dimensional association analyses

由 Roshchupkin, G.V, Adams, H.H.H, Vernooij, M.W, Hofman, A, Van Duijn, C.M, Ikram, M.A, Niessen, W.J
出版 2020

An IGF-I gene polymorphism modifies the risk of diabetic retinopathy

由 Rietveld, I, Ikram, M.K, Vingerling, J.R, Hofman, A, Pols, H.A.P, Lamberts, S.W.J, De Jong, P.T.V.M, Van Duijn, C.M, Janssen, J.A.M.J.L
出版 2020

Heritability of the shape of subcortical brain structures in the general population

由 Roshchupkin, G.V, Gutman, B.A, Vernooij, M.W, Jahanshad, N, Martin, N.G, Hofman, A, McMahon, K.L, Van Der Lee, S.J, Van Duijn, C.M, De Zubicaray, G.I, Uitterlinden, A.G, Wright, M.J, Niessen, W.J, Thompson, P.M, Ikram, M.A, Adams, H.H.H
出版 2020

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions

由 Hill, W.D, Davies, G, Harris, S.E, Hagenaars, S.P, Liewald, D.C, Penke, L, Gale, C.R, Deary, I.J, Debette, S, Verbaas, C.I, Bressler, J, Schuur, M, Smith, A.V, Bis, J.C, Bennett, D.A, Ikram, M.A, Launer, L.J, Fitzpatrick, A.L, Seshadri, S, Van Duijn, C.M, Mosley, T.H
出版 2020

Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic discarea

由 Khor, C.C., Ramdas, W.D., Vithana, E.N., Cornes, B.K., Sim, X., Tay, W.-T., Saw, S.-M., Lavanya, Y.Z., Wu, R., Wang, J.J., Mitchell, P., Uitterlinden, A.G., Rivadeneira, F., Teo, Y.-Y., Chia, K.-S., Seielstad, M., Hibberd, M., Vingerling, J.R., Klaver, C.C., Jansonius, N.M., Tai, E.-S., Wong, T.-Y., van Duijn, C.M., Aung, T.
出版 2014

A genome-wide association study of optic disc parameters

由 Ramdas W.D., van Koolwijk L.M.E., Ikram M.K., Jansonius N.M., de Jong P.T.V.M., Bergen A.A.B., Isaacs A., Amin N., Aulchenko Y.S., Wolfs R.C.W., Hofman A., Rivadeneira F., Oostra B.A., Uitterlinden A.G., Hysi P., Hammond C.J., Lemij H.G., Vingerling J.R., Klaver C.C.W., van Duijn C.M.
出版 2019

The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project

由 Combarros, O, Warden, D.R, Hammond, N, Cortina-Borja, M, Belbin, O, Lehmann, M.G, Wilcock, G.K, Brown, K, Kehoe, P.G, Barber, R, Coto, E, Alvarez, V, Deloukas, P, Gwilliam, R, Heun, R, Kölsch, H, Mateo, I, Oulhaj, A, Arias-Vásquez, A, Schuur, M, Aulchenko, Y.S, Ikram, M.A, Breteler, M.M, van Duijn, C.M, Morgan, K, Smith, A.D, Lehmann, D.J
出版 2020

Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis

由 Holliday, E.G., Smith, A.V., Cornes, B.K., Buitendijk, G.H.S., Jensen, R.A., Sim, X., Aspelund, T., Aung, T., Baird, P.N., Boerwinkle, E., Cheng, C.Y., van Duijn, C.M., Eiriksdottir, G., Gudnason, V., Harris, T., Hewitt, A.W., Inouye, M., Jonasson, F., Klein, B.E.K., Launer, L., Li, X., Liew, G., Lumley, T., McElduff, P., McKnight, B., Mitchell, P., Psaty, B.M., Rochtchina, E., Rotter, J.I., Scott, R.J., Tay, W., Taylor, K., Teo, Y.Y., Uitterlinden, A.G., Viswanathan, A., Xie, S., Vingerling, J.R., Klaver, C.C.W., Tai, E.S., Siscovick, D., Klein, R., Cotch, M.F., Wong, T.Y., Attia, J., Wang, J.J.
出版 2014

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course

由 Graff, M., Ngwa, J.S., Workalemahu, T., Homuth, G., Schipf, S., Teumer, A., Völzke, H., Wallaschofski, H., Abecasis, G.R., Edward, L., Francesco, C., Sanna, S., Scheet, P., Schlessinger, D., Sidore, C., Xiao, X., Wang, Z., Chanock, S.J., Jacobs, K.B., Hayes, R.B., Hu, F., Van Dam, R.M., Crout, R.J., Marazita, M.L., Shaffer, J.R., Atwood, L.D., Fox, C.S., Heard-Costa, N.L., White, C., Choh, A.C., Czerwinski, S.A., Demerath, E.W., Dyer, T.D., Towne, B., Amin, N., Oostra, B.A., Van Duijn, C.M., Zillikens, M.C., Esko, T., Nelis, M., Nikopensius, T., Metspalu, A., Strachan, D.P., Monda, K., Qi, L., North, K.E., Cupples, L.A., Gordon-Larsen, P., Berndt, S.I.
出版 2014

Genome-Wide Association Study of Retinopathy in Individuals without Diabetes

由 Jensen, R.A., Sim, X., Li, X., Cotch, M.F., Ikram, M.K., Holliday, E.G., Eiriksdottir, G., Harris, T.B., Jonasson, F., Klein, B.E.K., Launer, L.J., Smith, A.V., Boerwinkle, E., Cheung, N., Hewitt, A.W., Liew, G., Mitchell, P., Wang, J.J., Attia, J., Scott, R., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Taylor, K., Hofman, A., de Jong, P.T.V.M., Rivadeneira, F., Uitterlinden, A.G., Tay, W.-T., Teo, Y.Y., Seielstad, M., Liu, J., Cheng, C.-Y., Saw, S.-M., Aung, T., Ganesh, S.K., O'Donnell, C.J., Nalls, M.A., Wiggins, K.L., Kuo, J.Z., van Duijn, C.M., Gudnason, V., Klein, R., Siscovick, D.S., Rotter, J.I., Tai, E.S., Vingerling, J., Wong, T.Y.
出版 2014

Evaluation of presumably disease causing SCN1A variants in a cohort of common epilepsy syndromes

由 Lal D., Reinthaler E.M., Dejanovic B., May P., Thiele H., Lehesjoki A.-E., Schwarz G., Riesch E., Ikram M.A., Van Duijn C.M., Uitterlinden A.G., Hofman A., Steinböck H., Gruber-Sedlmayr U., Neophytou B., Zara F., Hahn A., Gormley P., Becker F., Weber Y.G., Cilio M.R., Kunz W.S., Krause R., Zimprich F., Lemke J.R., Nürnberg P., Sander T., Lerche H., Neubauer B.A., Palotie A., Ruppert A.-K., Suls A., Siren A., Koeleman B., Haberlandt E., Ronen G.M., Caglayan H., Hjalgrim H., Muhle H., Schulz H., Helbig I., Altmüller J., Geldner J., Schubert J., Jabbari K., Everett K., Feucht M., Balestri M., Nothnagel M., Striano P., Møller R.S., Nabbout R., Balling R., Baulac S., Bianchi A., La Neve A., Minetti C., Giuseppe C.
出版 2019

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci

由 Simpson C.L., Wojciechowski R., Oexle K., Murgia F., Portas L., Li X., Virginie J.M.V., Vitart V., Schache M., Mohsen Hosseini S., Hysi P.G., Raffel L.J., Cotch M.F., Chew E., Klein B.E.K., Klein R., Wong T.Y., Van Duijn C.M., Mitchell P., Saw S.M., Fossarello M., Wang J.J., Polašek O., Campbell H., Rudan I., Oostra B.A., Uitterlinden A.G., Hofman A., Rivadeneira F., Amin N., Karssen L.C., Vingerling J.R., Döring A., Bettecken T., Bencic G., Gieger C., Wichmann H.-E., Wilson J.F., Venturini C., Fleck B., Cumberland P.M., Rahi J.S., Hammond C.J., Hayward C., Wright A.F., Paterson A.D., Baird P.N., Klaver C.C.W., Rotter J.I., Pirastu M., Meitinger T., Bailey-Wilson J.E., Stambolian D.
出版 2018

Common genetic determinants of intraocular pressure and primary open-angle Glaucoma

由 van Koolwijk, L.M.E., Ramdas, W.D., Ikram, M.K., Jansonius, N.M., Pasutto, F., Hysi, P.G., Macgregor, S., Janssen, S.F., Hewitt, A.W., Viswanathan, A.C., ten Brink, J.B., Hosseini, S.M., Amin, N., Despriet, D.D.G., Willemse-Assink, J.J.M., Kramer, R., Rivadeneira, F., Struchalin, M., Aulchenko, Y.S., Weisschuh, N., Zenkel, M., Mardin, C.Y., Gramer, E., Welge-Lüssen, U., Montgomery, G.W., Carbonaro, F., Young, T.L., Bellenguez, C., McGuffin, P., Foster, P.J., Topouzis, F., Mitchell, P., Wang, J.J., Wong, T.Y., Czudowska, M.A., Hofman, A., Uitterlinden, A.G., Wolfs, R.C.W., de Jong, P.T.V.M., Oostra, B.A., Paterson, A.D., Mackey, D.A., Bergen, A.A.B., Reis, A., Hammond, C.J., Vingerling, J.R., Lemij, H.G., Klaver, C.C.W., van Duijn, C.M.
出版 2014

Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus

由 Strange, A., Bellenguez, C., Sim, X., Luben, R., Hysi, P.G., Ramdas, W.D., van Koolwijk, L.M., Freeman, C., Pirinen, M., Su, Z., Band, G., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S., Gray, E., Dronov, S., Potter, S.C., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, S.J., Blackwell, J.M., Bramon, E., Brown, M.A., Casas, J.P., Corvin, A., Duncanson, A., Jankowski, J.A., Markus, H.S., Mathew, C.G., Palmer, C.N., Plomin, R., Rautanen, A., Sawcer, S.J., Trembath, R.C., Wood, N.W., Barroso, I., Leena Peltonen, L.P., Healey, P., McGuffin, P., Topouzis, F., Klaver, C.C., van Duijn, C.M., Mackey, D.A., Young, T.L., Hammond, C.J., Khaw, K.-T., Wareham, N., Wang, J.J., Wong, T.Y., Foster, P.J., Mitchell, P., Spencer, C.C., Donnelly, P., Viswanathan, A.C.
出版 2014

Genetic Loci for Retinal Arteriolar Microcirculation

由 Sim, X., Jensen, R.A., Ikram, M.K., Cotch, M.F., Li, X., MacGregor, S., Xie, J., Smith, A.V., Boerwinkle, E., Mitchell, P., Klein, R., Klein, B.E.K., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., de Jong, P.T.V.M., Hofman, A., Rivadeneira, F., Uitterlinden, A.G., van Duijn, C.M., Aspelund, T., Eiriksdottir, G., Harris, T.B., Jonasson, F., Launer, L.J., Attia, J., Baird, P.N., Harrap, S., Holliday, E.G., Inouye, M., Rochtchina, E., Scott, R.J., Viswanathan, A., Li, G., Smith, N.L., Wiggins, K.L., Kuo, J.Z., Taylor, K.D., Hewitt, A.W., Martin, N.G., Montgomery, G.W., Sun, C., Young, T.L., Mackey, D.A., van Zuydam, N.R., Doney, A.S.F., Palmer, C.N.A., Morris, A.D., Rotter, J.I., Tai, E.S., Gudnason, V., Vingerling, J.R., Siscovick, D.S., Wang, J.J., Wong, T.Y.
出版 2014

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

由 Stambolian, D., Wojciechowski, R., Oexle, K., Pirastu, M., Li, X., Raffe, L.J., Cotch, M.F., Chew, E.Y., Klein, B., Klein, R., Wong, T.Y., Simpson, C.L., Klaver, C.C.W., van Duijn, C.M., Verhoeven, V.J.M., Baird, P.N., Vitart, V., Paterson, A.D., Mitchell, P., Saw, S.M., Fossarello, M., Kazmierkiewicz, K., Murgia, F., Portas, L., Schache, M., Richardson, A., Xie, J., Wang, J.J., Rochtchina, E., Viswanathan, A.C., Hayward, C., Wright, A.F., Polašek, O., Campbell, H., Rudan, I., Oostra, B.A., Uitterlinden, A.G., Hofman, A., Rivadeneira, F., Amin, N., Karssen, L.C., Vingerling, J.R., Hosseini, S.M., Döring, A., Bettecken, T., Vatavuk, Z., Gieger, C., Wichmann, H.-E., Wilson, J.F., Fleck, B., Foster, P.J., Topouzis, F., McGuffin, P., Sim, X., Inouye, M., Holliday, E.G., Attia, J., Scott, R.J., Rotter, J.I., Meitinger, T., Bailey-Wilson, J.E.
出版 2014

Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In vivo

由 Kamran Ikram, M., Xueling, S., Jensen, R.A., Cotch, M.F., Hewitt, A.W., Ikram, M.A., Wang, J.J., Klein, R., Klein, B.E.K., Breteler, M.M.B., Cheung, N., Liew, G., Mitchell, P., Uitterlinden, A.G., Rivadeneira, F., Hofman, A., de Jong, P.T.V.M., van Duijn, C.M., Kao, L., Cheng, C.-Y., Smith, A.V., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Jonasson, F., Eiriksdottir, G., Aspelund, T., Harris, T.B., Launer, L.J., Taylor, K.D., Li, X., Iyengar, S.K., Xi, Q., Sivakumaran, T.A., MacKey, D.A., MacGregor, S., Martin, N.G., Young, T.L., Bis, J.C., Wiggins, K.L., Heckbert, S.R., Hammond, C.J., Andrew, T., Fahy, S., Attia, J., Holliday, E.G., Scott, R.J., Islam, F.M.A., Rotter, J.I., McAuley, A.K., Boerwinkle, E., Tai, E.S., Gudnason, V., Siscovick, D.S., Vingerling, J.R., Wong, T.Y.
出版 2014

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

由 van der Lee, S.J., Knol, M.J., Chauhan, G., Satizabal, C.L., Smith, A.V., Hofer, E., Bis, J.C., Hibar, D.P., Hilal, S., van den Akker, E.B., Arfanakis, K., Bernard, M., Yanek, L.R., Amin, N., Crivello, F., Cheung, J.W., Harris, T.B., Saba, Y., Lopez, O.L., Li, S., van der Grond, J., Yu, L., Paus, T., Roshchupkin, G.V., Amouyel, P., Jahanshad, N., Taylor, K.D., Yang, Q., Mathias, R.A., Boehringer, S., Mazoyer, B., Rice, K., Cheng, C.Y., Maillard, P., van Heemst, D., Wong, T.Y., Niessen, W.J., Beiser, A.S., Beekman, M., Zhao, W., Nyquist, P.A., Chen, C., Launer, L.J., Psaty, B.M., Ikram, M.K., Vernooij, M.W., Schmidt, H., Pausova, Z., Becker, D.M., De Jager, P.L., Thompson, P.M., van Duijn, C.M., Bennett, D.A., Slagboom, P.E., Schmidt, R., Longstreth, W.T., Ikram, M.A., Seshadri, S., Debette, S., Gudnason, V., Adams, H.H.H., DeCarli, C.
出版 2021

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

由 King R., Struebing F.L., Li Y., Wang J., Koch A.A., Cooke Bailey J.N., Gharahkhani P., MacGregor S., Allingham R.R., Hauser M.A., Wiggs J.L., Geisert E.E., Brilliant M., Budenz D., Bailey J.C., Fingert J., Gaasterland D., Gaasterland T., Haines J.L., Hark L., Igo R., Kang J.H., Kraft P., Lee R., Lichter P., Liu Y., Moroi S., Pasquale L.R., Pericak-Vance M., Realini A., Rhee D., Richards J.R., Ritch R., Schuman J., Scott W.K., Singh K., Sit A., Vollrath D., Weinreb R.N., Wollstein G., Zack D., Aung T., Burdon K.P., Cheng C.-Y., Bailey J.N.C., Craig J.E., Cree A.J., Hammond C.J., Hewitt A.W., H?hn R., Hysi P., Gonzalez A.I.I., Jonas J., Khawaja A., Khor C.-C., Klaver C.C.W., Pasutto F., Mackey D., Mitchell P., Mishra A., Pang C., Springelkamp H., Thorleifsson G., Thorsteinsdottir U., van Duijn C.M., Viswanathan A., Vitart V., Wojciechowski R., Wong T., Young T.L., Zeller T.
出版 2020

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

由 Verhoeven, V.J.M., Hysi, P.G., Saw, S.-M., Vitart, V., Mirshahi, A., Guggenheim, J.A., Cotch, M.F., Yamashiro, K., Baird, P.N., Mackey, D.A., Wojciechowski, R., Kamran Ikram, M., Hewitt, A.W., Duggal, P., Janmahasatian, S., Khor, C.-C., Fan, Q., Zhou, X., Young, T.L., Tai, E.-S., Goh, L.-K., Li, Y.-J., Aung, T., Vithana, E., Teo, Y.-Y., Tay, W., Sim, X., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Campbell, H., Wilson, J.F., Fleck, B.W., Nakata, I., Yoshimura, N., Yamada, R., Matsuda, F., Ohno-Matsui, K., Nag, A., McMahon, G., St. Pourcain, B., Lu, Y., Rahi, J.S., Cumberland, P.M., Bhattacharya, S., Simpson, C.L., Atwood, L.D., Li, X., Raffel, L.J., Murgia, F., Portas, L., Despriet, D.D.G., Van Koolwijk, L.M.E., Wolfram, C., Lackner, K.J., Tönjes, A., Mägi, R., Lehtimäki, T., Kähönen, M., Esko, T., Metspalu, A., Rantanen, T., Pärssinen, O., Klein, B.E., Meitinger, T., Spector, T.D., Oostra, B.A., Smith, A.V., De Jong, P.T.V.M., Hofman, A., Amin, N., Karssen, L.C., Rivadeneira, F., Vingerling, J.R., Eiríksdóttir, G., Gudnason, V., Döring, A., Bettecken, T., Uitterlinden, A.G., Williams, C., Zeller, T., Castagné, R., Oexle, K., Van Duijn, C.M., Iyengar, S.K., Mitchell, P., Wang, J.J., Höhn, R., Pfeiffer, N., Bailey-Wilson, J.E., Stambolian, D., Wong, T.-Y., Hammond, C.J., Klaver, C.C.W.
出版 2014