Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy

• Main Authors: Mercer, Derry K., Torres, Marcelo D. T., Duay, Searle Aichelle S., Lovie, Emma, Simpson, Laura, von Köckritz-Blickwede, Maren, De la Fuente-Nunez, Cesar, O’Neil, Deborah A., Angeles-Boza, Alfredo M.
• Format: text
• Published: Animo Repository 2020
• Subjects: Peptide antibiotics; Microbial sensitivity tests; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11301
• Institution: De La Salle University

During the development of antimicrobial peptides (AMP) as potential therapeutics, antimicrobial susceptibility testing (AST) stands as an essential part of the process in identification and optimization of candidate AMP. Standard methods for AST, developed almost 60 years ago for testing conventiona...