Crystal structure of the acyltransferase domain of the iterative polyketide synthase in enediyne biosynthesis
Biosynthesis of the enediyne natural product dynemicin in Micromonospora chersina is initiated by DynE8, a highly reducing iterative type I polyketide synthase that assembles polyketide intermediates from the acetate units derived solely from malonyl-CoA. To understand the substrate specificity and...
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| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/104167 http://hdl.handle.net/10220/16984 |
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| Institution: | Nanyang Technological University |
| Language: | English |