Independent of EPR effect : a smart delivery nanosystem for tracking and treatment of nonvascularized intra-abdominal metastases

• Main Authors: Zhao, Lingzhi, Yuan, Wei, Li, Junyao, Yang, Liqiang, Su, Yaoquan, Peng, Juanjuan, Chen, Rui, Tham, Phoebe Huijun, Chen, Hongzhong, Lim, Wei Qi, Xiang, Huijing, Xing, Pengyao, Li, Fuyou, Zhao, Yanli
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Nanomedicine; Nanocarrier
• Online Access: https://hdl.handle.net/10356/137602
• Institution: Nanyang Technological University

Nanoparticle-based delivery systems (NDS) have impacted the field of cancer therapy on account of the enhanced permeability and retention (EPR) effect that promotes passive accumulation in tumors through the tumor vasculature after intravenous (IV) administration. However, transplanted tumor xenogra...