Efficient access to 2-pyrones via carbene-catalyzed oxidative [3+3] reactions between enals and nitrogen ylides

• Main Authors: Zheng, Pengcheng, Li, Chengcheng, Mou, Chengli, Pan, Dingwu, Wu, Shuquan, Xue, Wei, Jin, Zhichao, Chi, Robin Yonggui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry::Organic chemistry; NHC Catalysis; Enals
• Online Access: https://hdl.handle.net/10356/137778
• Institution: Nanyang Technological University

Pyrones are important structural units in natural products and synthetic functional molecules. Here, we report a carbene-catalyzed oxidative [3+3] cycloaddition reaction between enals and nitrogen ylides for quick access to 2-pyrones. Inexpensive and easily prepared 2′-pyridinium acetophenone bromid...