Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite

A new protocol for nucleophilic amination of methoxypyridines and their derivatives was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The method offers a concise access to various aminopyridines which are potentially of medicinal interest.

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Main Authors:	Pang, Jia Hao, Kaga, Atsushi, Chiba, Shunsuke
Other Authors:	School of Physical and Mathematical Sciences
Format:	Article
Language:	English
Published:	2020
Subjects:	Science::Chemistry Methoxypyridines Nucleophilic Amination
Online Access:	https://hdl.handle.net/10356/139533
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Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-139533
record_format	dspace
spelling	sg-ntu-dr.10356-1395332023-02-28T19:25:05Z Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite Pang, Jia Hao Kaga, Atsushi Chiba, Shunsuke School of Physical and Mathematical Sciences Science::Chemistry Methoxypyridines Nucleophilic Amination A new protocol for nucleophilic amination of methoxypyridines and their derivatives was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The method offers a concise access to various aminopyridines which are potentially of medicinal interest. MOE (Min. of Education, S’pore) Accepted version 2020-05-20T04:30:32Z 2020-05-20T04:30:32Z 2018 Journal Article Pang, J. H., Kaga, A., & Chiba, S. (2018). Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite. Chemical Communications, 54(73), 10324-10327. doi:10.1039/C8CC05979A 1359-7345 https://hdl.handle.net/10356/139533 10.1039/C8CC05979A 54 2-s2.0-85053297157 73 54 10324 10327 en Chemical Communications © 2018 Royal Society of Chemistry. All rights reserved. This paper was published in Chemical Communications and is made available with permission of Royal Society of Chemistry. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Chemistry Methoxypyridines Nucleophilic Amination
spellingShingle	Science::Chemistry Methoxypyridines Nucleophilic Amination Pang, Jia Hao Kaga, Atsushi Chiba, Shunsuke Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
description	A new protocol for nucleophilic amination of methoxypyridines and their derivatives was developed using sodium hydride (NaH) in the presence of lithium iodide (LiI). The method offers a concise access to various aminopyridines which are potentially of medicinal interest.
author2	School of Physical and Mathematical Sciences
author_facet	School of Physical and Mathematical Sciences Pang, Jia Hao Kaga, Atsushi Chiba, Shunsuke
format	Article
author	Pang, Jia Hao Kaga, Atsushi Chiba, Shunsuke
author_sort	Pang, Jia Hao
title	Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
title_short	Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
title_full	Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
title_fullStr	Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
title_full_unstemmed	Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
title_sort	nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite
publishDate	2020
url	https://hdl.handle.net/10356/139533
_version_	1759853968385638400

Nucleophilic amination of methoxypyridines by a sodium hydride-iodide composite

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