Structural and biochemical studies of erythromycin-resistance methyltransferases : insights into structure-based drug design
Erm38 is a methyltransferase from Mycolicibacterium smegmatis that methylates the A2058 position in 23S rRNA using S-adenosyl methionine (SAM) as methyl donor. It confers resistance to macrolides, lincosamides and streptogramins in Gram-positive bacteria and mycobacteria. In this project, we obtaine...
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| 格式: | Final Year Project |
| 語言: | English |
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Nanyang Technological University
2020
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| 在線閱讀: | https://hdl.handle.net/10356/140816 |
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