Capsule-like safe genetic vectors — cell-penetrating core – shell particles selectively release functional small RNA and entrap its encoding DNA
The breakthrough of genetic therapy is set back by the lack of suitable genetic vector systems. We present the development of permeability-tunable, capsule-like, polymeric, micron-sized, core–shell particles for delivery of recombinant nucleic acids into target cells. These particles were demonstrat...
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Main Authors: | Yu, Han, Pan, Matthew Houwen, Evalin, Trau, Dieter, Patzel, Volker |
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Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/141342 |
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Institution: | Nanyang Technological University |
Language: | English |
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