Chromatin interactions and regulatory elements in cancer : from bench to bedside

Chromatin interactions regulate gene expression by bringing distal regulatory elements, such as super-enhancers, to promoters in close spatial proximity. It has been recognized that in cancer, chromatin interactions can be dysregulated, leading to aberrant oncogene expression. Chromatin interactions...

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Bibliographic Details
Main Authors: See, Yi Xiang, Wang, Benny Zhengjie, Fullwood, Melissa Jane
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/144387
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Institution: Nanyang Technological University
Language: English