Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites

Conserved sequence motifs in human TMTC1, TMTC2, TMTC3, and TMTC4, new O-mannosyltransferases from the GT-C/PMT clan, are rationalized as ligand binding sites

Background: The human proteins TMTC1, TMTC2, TMTC3 and TMTC4 have been experimentally shown to be components of a new O-mannosylation pathway. Their own mannosyl-transferase activity has been suspected but their actual enzymatic potential has not been demonstrated yet. So far, sequence analysis of T...

Full description

Saved in:
Bibliographic Details
Main Authors: Eisenhaber, Birgit, Sinha, Swati, Jadalanki, Chaitanya K., Shitov, Vladimir A., Tan, Qiao Wen, Sirota, Fernanda L., Eisenhaber, Frank
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
TMTC1
TMTC2
Online Access:https://hdl.handle.net/10356/146664
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/146664

Similar Items