Iterative addition of carbon nucleophiles toN,N-dialkyl carboxamides for synthesis of α-tertiary amines

A protocol for the synthesis of α-tertiary amines was developed by iterative addition of carbon nucleophiles toN,N-dialkyl carboxamides. Nucleophilic 1,2-addition of organolithium reagents to carboxamides forms anionic tetrahedral carbinolamine (hemiaminal) intermediates, which are subsequently trea...

全面介紹

Saved in:
書目詳細資料
Main Authors: Chen, Jiahua, Lim, Jun Wei, Ong, Derek Yiren, Chiba, Shunsuke
其他作者: School of Physical and Mathematical Sciences
格式: Article
語言:English
出版: 2022
主題:
在線閱讀:https://hdl.handle.net/10356/154825
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!