A modular approach to enzymatic ligation of peptides and proteins with oligonucleotides

Joining peptides and oligonucleotides offers potential benefits, but current methods remain laborious. Here we present a novel approach towards enzymatic ligation of the two modalities through the development of tag phosphoramidites that readily couple onto oligonucleotides. This simple and highly e...

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Bibliographic Details
Main Authors: Tan, Derrick Jing Yang, Cheong, Vee Vee, Lim, Kah Wai, Phan, Anh Tuân
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/158325
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Institution: Nanyang Technological University
Language: English