A renal-clearable macromolecular reporter for near-infrared fluorescence imaging of bladder cancer

• Main Authors: Huang, Jiaguo, Jiang, Yuyan, Li, Jingchao, He, Shasha, Huang, Jingsheng, Pu, Kanyi
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Chemical engineering; Bladder Cancer; Fluorescence Imaging
• Online Access: https://hdl.handle.net/10356/162026
• Institution: Nanyang Technological University

Bladder cancer (BC) is a prevalent disease with high morbidity and mortality; however, in vivo optical imaging of BC remains challenging because of the lack of cancer-specific optical agents with high renal clearance. Herein, a macromolecular reporter (CyP1) was synthesized for real-time near-infrar...