Role of the VCA domain of WASP in filopodia formation.

• Main Author: Gunaseelan Narayanan.
• Other Authors: Thirumaran s/o Thanabalu
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/16330
• Institution: Nanyang Technological University

Wiskott-Aldrich syndrome protein (WASP) is implicated in Wiskott-Aldrich Syndrome (WAS), which is a genetic disorder. The Verprolin Cofilin Acidic (VCA) domain of WASP can activate the Actin-related protein2/3 (Arp2/3) complex but whether this property is associated with the possible ability of WASP...