Activatable Mn²⁺-armed nanoagonist augments antitumor immunity in colorectal cancer: a NIR-II photonic neoadjuvant paradigm

• Main Authors: Liang, Qing, Chen, Jiayuan, Hou, Shuai, Li, Di, Zhu, Ying, Li, Ruiqi, Chen, Lian, Li, Jiao, Fu, Wei, Lei, Shiqiong, Zhang, Biying, Zheng, Xin, Zhang, Tao, Duan, Hongwei, He, Wenshan, Ren, Jinghua
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Bioengineering; Nanoagonist; Neoadjuvant Therapy
• Online Access: https://hdl.handle.net/10356/170067
• Institution: Nanyang Technological University

Postoperative recurrence frequently occurs in patients with colorectal cancer (CRC) due to residual microtumors and host cellular immune dysfunction, leading to major setbacks in clinical outcomes and CRC staging. As an increasingly prevalent therapeutic option for CRC patients, neoadjuvant chemorad...