Catalytic regioselective acylation of unprotected nucleosides for quick access to COVID and other nucleoside prodrugs
Nucleosides have important therapeutic applications that include antiviral activities against COVID viruses. It is a common strategy to convert one or multiple of the hydroxyl (OH) units in nucleosides to the corresponding ester groups to prepare nucleoside prodrugs for better performance. Due to th...
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Main Authors: | , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/171236 |
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Institution: | Nanyang Technological University |
Language: | English |