Catalytic regioselective acylation of unprotected nucleosides for quick access to COVID and other nucleoside prodrugs

Catalytic regioselective acylation of unprotected nucleosides for quick access to COVID and other nucleoside prodrugs

Nucleosides have important therapeutic applications that include antiviral activities against COVID viruses. It is a common strategy to convert one or multiple of the hydroxyl (OH) units in nucleosides to the corresponding ester groups to prepare nucleoside prodrugs for better performance. Due to th...

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Bibliographic Details
Main Authors: Lv, Jie, Zou, Juan, Nong, Yingling, Song, Jia, Shen, Tingwei, Cai, Hui, Mou, Chengli, Lyu, Wenxin, Jin, Zhichao, Chi, Robin Yonggui
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Article
Language:English
Published: 2023
Subjects:
Science::Chemistry
Pentose Functionalization
Regioselective
Online Access:https://hdl.handle.net/10356/171236
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/171236

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