Molecular phenotyping of single pancreatic islet leader beta cells by "Flash-Seq"
Aims: Spatially-organized increases in cytosolic Ca2+ within pancreatic beta cells in the pancreatic islet underlie the stimulation of insulin secretion by high glucose. Recent data have revealed the existence of subpopulations of beta cells including “leaders” which initiate Ca2+ waves. Whether lea...
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Main Authors: | Chabosseau, Pauline, Yong, Fiona, Delgadillo-Silva, Luis F., Lee, Eun Young, Melhem, Rana, Li, Shiying, Gandhi, Nidhi, Wastin, Jules, Noriega, Livia Lopez, Leclerc, Isabelle, Ali, Yusuf, Hughes, Jing W., Sladek, Robert, Martinez-Sanchez, Aida, Rutter, Guy A. |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/171807 |
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Institution: | Nanyang Technological University |
Language: | English |
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