Dengue and Zika RNA-RNA interactomes reveal pro- and anti-viral RNA in human cells

• Main Authors: Liao, Kuo-Chieh, Xie, Xuping, Sundstrom, Anna Karin Beatrice, Lim, Xin Ni, Tan, Kiat Kee, Zhang, Yu, Zou, Jing, Bifani, Amanda Makha, Poh, Hui Xian, Chen, Jia Jia, Ng, Wy Ching, Lim, Su Ying, Ooi, Eng Eong, Sessions, October M., Tay, Yvonne, Shi, Pei-Yong, Huber, Roland G., Wan, Yue
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2024
• Subjects: Medicine, Health and Life Sciences; Dengue; Zika virus
• Online Access: https://hdl.handle.net/10356/173772
• Institution: Nanyang Technological University

Background: Identifying host factors is key to understanding RNA virus pathogenicity. Besides proteins, RNAs can interact with virus genomes to impact replication. Results: Here, we use proximity ligation sequencing to identify virus-host RNA interactions for four strains of Zika virus (ZIKV) and on...