Enones from aldehydes and alkenes by carbene-catalyzed dehydrogenated couplings

• Main Authors: Tang, Kun, Su, Fen, Pan, Shijie, Lu, Fengfei, Luo, Zhongfu, Che, Fengrui, Wu, Xingxing, Chi, Robin Yonggui
• Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
• Format: Article
• Language: English
• Published: 2024
• Subjects: Agricultural Sciences; Enones; Cross dehydrogenative coupling
• Online Access: https://hdl.handle.net/10356/174241
• Institution: Nanyang Technological University

A new class of chiral pyranone fused indole derivatives were prepared by means of N-heterocyclic carbene (NHC) organocatalysis and demonstrated notable antibacterial activity against Xanthomonas oryzae pv oryzae (Xoo). Bioassays showed that compounds (3S,4R)-5b, (3S,4R)-5d, and (3S,4R)-5l exhibited...