Plasmodium falciparum eukaryotic translation initiation factor 3 is stabilized by quinazoline-quinoline bisubstrate inhibitors
Malaria drug resistance is hampering the fight against the deadliest parasitic disease affecting over 200 million people worldwide. We recently developed quinoline-quinazoline-based inhibitors (as compound 70) as promising new antimalarials. Here, we aimed to investigate their mode of action by usin...
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| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/174270 |
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| Institution: | Nanyang Technological University |
| Language: | English |