Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer's disease mouse model
Macrophages accumulate lipid droplets (LDs) under stress and inflammatory conditions. Despite the presence of LD-loaded macrophages in many tissues, including the brain, their contribution to neurodegenerative disorders remains elusive. This study investigated the role of lipid metabolism in Alzheim...
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Main Authors: | Wu, Xiaoting, Miller, James Alastair, Lee, Bernett Teck Kwong, Wang, Yulan, Ruedl, Christiane |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2025
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/184421 |
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