Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer's disease mouse model

Macrophages accumulate lipid droplets (LDs) under stress and inflammatory conditions. Despite the presence of LD-loaded macrophages in many tissues, including the brain, their contribution to neurodegenerative disorders remains elusive. This study investigated the role of lipid metabolism in Alzheim...

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Bibliographic Details
Main Authors: Wu, Xiaoting, Miller, James Alastair, Lee, Bernett Teck Kwong, Wang, Yulan, Ruedl, Christiane
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2025
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Online Access:https://hdl.handle.net/10356/184421
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