Computational analysis of differential interactions between cyclins and CDKs.

• Main Author: See, Pui Fun.
• Other Authors: Chandra Shekhar Verma
• Format: Final Year Project
• Language: English
• Published: 2010
• Subjects: DRNTU::Science::Biological sciences::Biomathematics
• Online Access: http://hdl.handle.net/10356/38812
• Institution: Nanyang Technological University

Members of cyclin-dependent kinase (CDKs) family in complex with their cognate regulatory subunits, cyclins, have been implicated in the control of essential cellular activities. Recent gene-targeted knockout studies performed on different cyclin-CDK complexes opposes the ‘classical model’ of cell-c...