Dissection of mechanistic action of anticancer multidrug resistance reversal agents from a natural product library.
The phenomenon of multidrug resistant (MDR) ovarian cancer is a major obstacle to successful cancer treatment. Thapsigargin, a natural sesquiterpene lactone, has been studied for its MDR reversal effects against MDR cancers by inducing endoplasmic recticulum stress and cell death. In this study, we...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2010
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| Online Access: | http://hdl.handle.net/10356/39580 |
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| Institution: | Nanyang Technological University |
| Language: | English |