Synthetic route to quinolines via microwave irradiation assisted triflic acid-catalyzed friedländer annulation.

Synthetic route to quinolines via microwave irradiation assisted triflic acid-catalyzed friedländer annulation.

An efficient triflic acid-catalyzed Friedländer annulation of 2-aminobenzophenone and ketone to afford quinolines under microwave irradiation is reported herein. The methodology gives a variety of quinolines with moderate to high yields (30-90%), achieved with 5 mol% of the Brønsted acid.

Saved in:
Bibliographic Details
Main Author: Hoeng, Murni.
Other Authors: Philip Wai Hong Chan
Format: Final Year Project
Language:English
Published: 2010
Subjects:
DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
Online Access:http://hdl.handle.net/10356/39834
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Description
Summary:An efficient triflic acid-catalyzed Friedländer annulation of 2-aminobenzophenone and ketone to afford quinolines under microwave irradiation is reported herein. The methodology gives a variety of quinolines with moderate to high yields (30-90%), achieved with 5 mol% of the Brønsted acid.

Similar Items