Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA
Some sequences of DNA that possess certain guanine or cytosine-riched stretches are capable of associating into two types of four-stranded DNA structures, namely G-quadruplex and i-motif respectively, which could exist in some biologically important regions of DNA such as the end of chromosomes a...
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sg-ntu-dr.10356-424372023-02-28T23:38:21Z Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA Luo, Ji School of Physical and Mathematical Sciences Li Tianhu DRNTU::Science::Chemistry::Biochemistry Some sequences of DNA that possess certain guanine or cytosine-riched stretches are capable of associating into two types of four-stranded DNA structures, namely G-quadruplex and i-motif respectively, which could exist in some biologically important regions of DNA such as the end of chromosomes and the regulatory regions of oncogenes. With the aim of exploring new properties and applications of quadruplex DNA during my graduate studies, we have investigated the factors that affect the G-quadruplex that could undergo self-cleavage reactions, and developed certain fluorescence-tagged circular i-motifs to be used as molecular probes. Master of Science 2010-12-02T07:07:16Z 2010-12-02T07:07:16Z 2010 2010 Thesis http://hdl.handle.net/10356/42437 en 109 p. application/pdf |
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DRNTU::Science::Chemistry::Biochemistry Luo, Ji Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA |
| description |
Some sequences of DNA that possess certain guanine or cytosine-riched stretches are
capable of associating into two types of four-stranded DNA structures, namely
G-quadruplex and i-motif respectively, which could exist in some biologically important regions of DNA
such as the end of chromosomes and the regulatory regions of oncogenes. With the aim of
exploring new properties and applications of quadruplex DNA during my graduate studies,
we have investigated the factors that affect the G-quadruplex that could undergo
self-cleavage reactions, and developed certain fluorescence-tagged circular i-motifs to be
used as molecular probes. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Luo, Ji |
| format |
Theses and Dissertations |
| author |
Luo, Ji |
| author_sort |
Luo, Ji |
| title |
Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA |
| title_short |
Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA |
| title_full |
Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA |
| title_fullStr |
Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA |
| title_full_unstemmed |
Investigation of new properties and applications of g-quadruplex DNA and I-motif DNA |
| title_sort |
investigation of new properties and applications of g-quadruplex dna and i-motif dna |
| publishDate |
2010 |
| url |
http://hdl.handle.net/10356/42437 |
| _version_ |
1759854369976614912 |