Highly stereoselective synthesis of tetrahydro-1,2-oxazines and bicyclic isoxazolidines from nitroso benzenes and 5-alkenylaldehydes

• Main Author: Zhu, Di
• Other Authors: Zhong Guofu
• Format: Theses and Dissertations
• Language: English
• Published: 2011
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/46316
• Institution: Nanyang Technological University

In 2000, List and co-workers firstly reported that L-proline was an effective asymmetric catalyst for the direct aldol reaction between unmodified acetone an a variety of aldehydes, with yields and enantioselectivities from moderate to good. This discovery has initiated the explosive growth of resea...