Characterization of sortase a expression in enterococcus faecalis.

• Main Author: Choo, Pei Yi.
• Other Authors: Kimberly Ann Kline
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Microbiology
• Online Access: http://hdl.handle.net/10356/52701
• Institution: Nanyang Technological University

Gram-positive bacteria rely on a family of sorting enzymes called sortases to attach cell surface proteins, often virulence factors, to their peptidoglycan cell wall. Two classes of sortase enzyme exist in Enterococcus faecalis, sortase A (SrtA) and sortase C (SrtC). Understanding these enzymes will...