Role of sphingosine kinase in the expression of adhesion molecules on monocytes induced by tumor necrosis factor-alpha : relevance to atherosclerosis

• المؤلف الرئيسي: Tuang, Chew Yan.
• مؤلفون آخرون: School of Mechanical and Aerospace Engineering
• التنسيق: Theses and Dissertations
• منشور في: 2008
• الموضوعات: DRNTU::Engineering::Mechanical engineering::Bio-mechatronics
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/5313

In this project, the effect of TNFa on the expression of ICAM-1 and (31 integrin (receptor of endothelial VCAM-1) on monocytes (U937 cells) was studied. In addition, an attempt was made to investigate the involvement of SPHK in this TNFa signaling pathway and to identify the mediators involved in th...