Adaptive evolution of pseudomonas aeruginosa during long-term co-culture with macrophages

• Main Author: Ding, Yichen
• Other Authors: Yang Liang
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Bacteria
• Online Access: http://hdl.handle.net/10356/53819
• Institution: Nanyang Technological University

Adaptive evolution of bacterial pathogens to the host environment is critical for their success during long-term infections. Previous studies have shown that adaptation of Pseudomonas aeruginosa did occur during chronic infections, which is probably driven by physical conditions, and the ho...