Using colloidal disassembly to determine molecular stability of DNA-coated magnetic micro-particles

• Main Author: Tan, Keith Wei Rong
• Other Authors: Phan Anh Tuan
• Format: Final Year Project
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences::Biophysics
• Online Access: http://hdl.handle.net/10356/74927
• Institution: Nanyang Technological University

Recently, methods to control the strength of the inter-bead interaction when using DNA G-quadruplexes to link magnetic micro-beads were explored and established. Using those techniques, we propose a method to assess the e ectiveness of G-quadruplex ligands by studying it's e ect on the colloi...