Intracellular delivery of antisense peptide nucleic acid by fluorescent mesoporous silica nanoparticles
In order to overcome poor cell permeability of antisense peptide nucleic acid (PNA), a fluorescent mesoporous silica nanoparticle (MSNP) carrier was developed to successfully deliver antisense PNA into cancer cells for effective silence of B-cell lymphoma 2 (Bcl-2) protein expression in vitro. First...
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Main Authors: | Ma, Xing, Qu, Qiuyu, Devi, Gitali, Toh, Desiree-Faye Kaixin, Chen, Gang, Zhao, Yanli |
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Other Authors: | School of Materials Science & Engineering |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/79499 http://hdl.handle.net/10220/24576 |
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Institution: | Nanyang Technological University |
Language: | English |
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