Predicting DNA sequence motifs of recombination hotspots by integrative visualization and analysis

• Main Authors: Khil, Pavel P., Przytycka, Teresa M., Yang, Peng, Wu, Min, Kwoh, Chee Keong, R. Daniel Camerini-Otero, Zheng, Jie
• 其他作者: School of Computer Engineering
• 格式: Conference or Workshop Item
• 語言: English
• 出版: 2013
• 主題: DRNTU::Engineering::Computer science and engineering::Software
• 在線閱讀: https://hdl.handle.net/10356/83920; http://hdl.handle.net/10220/18173

Meiotic recombination hotspots play important roles in life sciences, but the regulatory mechanism remain unclear. To predict DNA sequence motifs that regulate recombination hotspots, we designed an open source software tool called “LDsplit” that detects SNPs (single nucleotide polymorphisms) assoc...