Palladium-Catalyzed Asymmetric α-Arylation of Alkylnitriles

• المؤلفون الرئيسيون: Jiao, Zhiwei, Chee, Kwok Wei, Zhou, Jianrong Steve
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Palladium catalysis; Alkylnitrile
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/84965; http://hdl.handle.net/10220/43605

Asymmetric arylation of alkylnitriles forms quaternary stereocenters in good enantiocontrol for the first time. A lithium heterodimer consisting of an alkylnitrile anion and a disilylamide ion is the actual species responsible for the stereodetermining transmetalation in the catalytic cycle.