Porcine hepatocytes culture on biofunctionalized 3D inverted colloidal crystal scaffolds as an in vitro model for predicting drug hepatotoxicity
As drug-induced hepatotoxicity represents one of the most common causes of drug failure, three-dimensional (3D) in vitro liver platforms represent a fantastic toolbox to predict drug toxicity and thus reduce in vivo animal studies and lessen drug attrition rates. The aim of this study is to establis...
Saved in:
Main Authors: | Wu, Lingyan, Ferracci, Gaia, Wang, Yan, Fan, Teng Fei, Cho, Nam-Joon, Chow, Pierce K. H. |
---|---|
Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2019
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/85716 http://hdl.handle.net/10220/49833 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Hypothermia Advocates Functional Mitochondria and Alleviates Oxidative Stress to Combat Acetaminophen-Induced Hepatotoxicity
by: Tan, Y.L., et al.
Published: (2021) -
Bioactivation and hepatotoxicity of nitroaromatic drugs
by: Boelsterli, U.A., et al.
Published: (2011) -
Bioactivation and hepatotoxicity of nitroaromatic drugs
by: Boelsterli, U.A., et al.
Published: (2014) -
Acetaminophen psi parameter: a useful tool to quantify hepatotoxicity risk in acute acetaminophen overdose
by: Summon Chomchai, et al.
Published: (2015) -
Role of oxidative stress and mitochondrial changes in cyanobacteria-induced apoptosis and hepatotoxicity
by: Ding, W.-X., et al.
Published: (2012)