Rapid purification of sub-micrometer particles for enhanced drug release and microvesicles isolation

• Main Authors: Tay, Hui Min, Kharel, Sharad, Dalan, Rinkoo, Chen, Zhijie Joshua, Tan, Kah Kee, Boehm, Bernhard Otto, Loo, Say Chye Joachim, Hou, Han Wei
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Sub-micrometer Particles; Drug Release
• Online Access: https://hdl.handle.net/10356/85809; http://hdl.handle.net/10220/43855
• Institution: Nanyang Technological University

Efficient separation of sub-micrometer synthetic or biological components is imperative in particle-based drug delivery systems and purification of extracellular vesicles for point-of-care diagnostics. Herein, we report a novel phenomenon in spiral inertial microfluidics, in which the particle trans...