Essential role of the flexible linker on the conformational equilibrium of bacterial peroxiredoxin reductase for effective regeneration of peroxiredoxin

Reactive oxygen species (ROS) can damage DNA, proteins, and lipids, so cells have antioxidant systems that regulate ROS. In many bacteria, a dedicated peroxiredoxin reductase, alkyl hydroperoxide reductase subunit F (AhpF), catalyzes the rapid reduction of the redox-active disulfide center of the an...

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Bibliographic Details
Main Authors: Grüber, Gerhard, Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank
Other Authors: School of Computer Science and Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87081
http://hdl.handle.net/10220/44312
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Institution: Nanyang Technological University
Language: English