In Vitro Evaluation of Biofilm Dispersal as a Therapeutic Strategy To Restore Antimicrobial Efficacy

As a proof-of-concept study, the direct impact of biofilm dispersal on the in vitro efficacy of imipenem and tobramycin was evaluated against 3-day-old biofilms of Pseudomonas aeruginosa. Arabinose induction of biofilm dispersal via activation of the phosphodiesterase YhjH in the P. aeruginosa engin...

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Bibliographic Details
Main Authors: Roizman, Dan, Vidaillac, Celine, Givskov, Michael, Yang, Liang
Other Authors: Interdisciplinary Graduate School (IGS)
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87235
http://hdl.handle.net/10220/44364
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Institution: Nanyang Technological University
Language: English

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