Palladium‐Catalyzed Direct Cyclopropylation of Heterocycles

Many 1,3‐azoles and thiophenes are directly cyclopropylated in the presence of a simple palladium catalyst. The relative configuration on the three‐membered rings is retained in the products. Thus, the cyclopropyl–halide bond undergoes concerted oxidative addition to palladium(0) and cyclopropyl rad...

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Bibliographic Details
Main Authors: Wu, Xiaojin, Lei, Chuanhu, Yue, Guizhou, Zhou, Jianrong (Steve)
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/89367
http://hdl.handle.net/10220/44889
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Institution: Nanyang Technological University
Language: English