Factors influencing polycation/siRNA colloidal stability toward aerosol lung delivery
Hexanediol diacrylate cross-linked oligoethylenimine (OEI-HD) is a non-viral polymeric vector designed to deliver siRNA. To achieve safe and effective in vivo siRNA delivery using this vector, the polyplex must have sufficient colloidal stability if administered intravenously or nebulized for delive...
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Main Authors: | Steele, Terry W. J., Zhao, Xiaobin, Tarcha, Peter, Kissel, Thomas |
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Other Authors: | School of Materials Science & Engineering |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/99404 http://hdl.handle.net/10220/16219 |
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Institution: | Nanyang Technological University |
Language: | English |
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