Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity

Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity

10.1371/journal.pone.0010868

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Bibliographic Details
Main Authors:	Panchanathan R., Shen H., Zhang X., Ho S., Choubey D.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2019
Subjects:	alpha interferon estrogen estrogen receptor alpha gamma interferon messenger RNA STAT1 protein animal cell animal cell culture article autoimmunity cell stimulation controlled study female gender bias gene expression regulation gene function gene targeting genetic association immunoregulation interferon induction intracellular signaling male mouse nonhuman positive feedback promoter region protein expression receptor upregulation spleen cell steady state systemic lupus erythematosus transcription initiation transcription regulation wild type Animals Autoimmunity Cell Line, Tumor Estradiol Estrogen Receptor alpha Feedback, Physiological Female Gene Expression Regulation, Neoplastic Interferons Male Mice Mice, Inbred C57BL RNA, Messenger Sex Characteristics Signal Transduction STAT1 Transcription Factor Transcription, Genetic Murinae Mus
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161809
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Institution:	National University of Singapore

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Summary:	10.1371/journal.pone.0010868