Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity

10.1371/journal.pone.0010868

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Main Authors: Panchanathan R., Shen H., Zhang X., Ho S., Choubey D.
Other Authors: MICROBIOLOGY AND IMMUNOLOGY
Format: Article
Published: 2019
Subjects:
Mus
Online Access:https://scholarbank.nus.edu.sg/handle/10635/161809
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spelling sg-nus-scholar.10635-1618092024-03-27T08:17:18Z Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity Panchanathan R. Shen H. Zhang X. Ho S. Choubey D. MICROBIOLOGY AND IMMUNOLOGY alpha interferon estrogen estrogen receptor alpha gamma interferon messenger RNA STAT1 protein animal cell animal cell culture article autoimmunity cell stimulation controlled study female gender bias gene expression regulation gene function gene targeting genetic association immunoregulation interferon induction intracellular signaling male mouse nonhuman positive feedback promoter region protein expression receptor upregulation spleen cell steady state systemic lupus erythematosus transcription initiation transcription regulation wild type Animals Autoimmunity Cell Line, Tumor Estradiol Estrogen Receptor alpha Feedback, Physiological Female Gene Expression Regulation, Neoplastic Interferons Male Mice Mice, Inbred C57BL RNA, Messenger Sex Characteristics Signal Transduction STAT1 Transcription Factor Transcription, Genetic Murinae Mus 10.1371/journal.pone.0010868 PLoS ONE 5 5 e10868 2019-11-07T08:01:35Z 2019-11-07T08:01:35Z 2010 Article Panchanathan R., Shen H., Zhang X., Ho S., Choubey D. (2010). Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity. PLoS ONE 5 (5) : e10868. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0010868 19326203 https://scholarbank.nus.edu.sg/handle/10635/161809 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic alpha interferon
estrogen
estrogen receptor alpha
gamma interferon
messenger RNA
STAT1 protein
animal cell
animal cell culture
article
autoimmunity
cell stimulation
controlled study
female
gender bias
gene expression regulation
gene function
gene targeting
genetic association
immunoregulation
interferon induction
intracellular signaling
male
mouse
nonhuman
positive feedback
promoter region
protein expression
receptor upregulation
spleen cell
steady state
systemic lupus erythematosus
transcription initiation
transcription regulation
wild type
Animals
Autoimmunity
Cell Line, Tumor
Estradiol
Estrogen Receptor alpha
Feedback, Physiological
Female
Gene Expression Regulation, Neoplastic
Interferons
Male
Mice
Mice, Inbred C57BL
RNA, Messenger
Sex Characteristics
Signal Transduction
STAT1 Transcription Factor
Transcription, Genetic
Murinae
Mus
spellingShingle alpha interferon
estrogen
estrogen receptor alpha
gamma interferon
messenger RNA
STAT1 protein
animal cell
animal cell culture
article
autoimmunity
cell stimulation
controlled study
female
gender bias
gene expression regulation
gene function
gene targeting
genetic association
immunoregulation
interferon induction
intracellular signaling
male
mouse
nonhuman
positive feedback
promoter region
protein expression
receptor upregulation
spleen cell
steady state
systemic lupus erythematosus
transcription initiation
transcription regulation
wild type
Animals
Autoimmunity
Cell Line, Tumor
Estradiol
Estrogen Receptor alpha
Feedback, Physiological
Female
Gene Expression Regulation, Neoplastic
Interferons
Male
Mice
Mice, Inbred C57BL
RNA, Messenger
Sex Characteristics
Signal Transduction
STAT1 Transcription Factor
Transcription, Genetic
Murinae
Mus
Panchanathan R.
Shen H.
Zhang X.
Ho S.
Choubey D.
Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity
description 10.1371/journal.pone.0010868
author2 MICROBIOLOGY AND IMMUNOLOGY
author_facet MICROBIOLOGY AND IMMUNOLOGY
Panchanathan R.
Shen H.
Zhang X.
Ho S.
Choubey D.
format Article
author Panchanathan R.
Shen H.
Zhang X.
Ho S.
Choubey D.
author_sort Panchanathan R.
title Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity
title_short Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity
title_full Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity
title_fullStr Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity
title_full_unstemmed Mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: Implications for sex bias in autoimmunity
title_sort mutually positive regulatory feedback loop between interferons and estrogen receptor-? in mice: implications for sex bias in autoimmunity
publishDate 2019
url https://scholarbank.nus.edu.sg/handle/10635/161809
_version_ 1795300780786319360