Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

10.1186/s13045-017-0507-y

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Main Authors:	Zhou, J, Bi, C, Ching, Y.Q, Chooi, J.-Y, Lu, X, Quah, J.Y, Toh, S.H.-M, Chan, Z.-L, Tan, T.Z, Chong, P.S, Chng, W.-J
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2020
Subjects:	let 7a LIN28B protein microRNA stem cell factor unclassified drug LIN28B protein, human mirnlet7 microRNA, human RNA binding protein small interfering RNA acute myeloid leukemia animal experiment animal model animal tissue Article bioinformatics cancer inhibition carcinogenicity cell cycle arrest cell metabolism cell proliferation colony formation controlled study female G2 phase cell cycle checkpoint gene gene function gene overexpression gene silencing gene targeting genetic association hematopoiesis human human cell IGF2BP1 gene in vivo study KDM4A gene leukemia cell leukemogenesis LIN28B gene microarray analysis mouse nonhuman oncogene PSAT1 gene signal transduction tumor xenograft animal cell cycle checkpoint gene expression regulation genetics metabolism nonobese diabetic mouse pathology RNA interference SCID mouse tumor cell line Animals Cell Cycle Checkpoints Cell Line, Tumor Cell Proliferation Female Gene Expression Regulation, Leukemic Humans Leukemia, Myeloid, Acute Mice Mice, Inbred NOD Mice, SCID MicroRNAs RNA Interference RNA, Small Interfering RNA-Binding Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/173782
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1737822024-04-18T03:08:04Z Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia Zhou, J Bi, C Ching, Y.Q Chooi, J.-Y Lu, X Quah, J.Y Toh, S.H.-M Chan, Z.-L Tan, T.Z Chong, P.S Chng, W.-J CANCER SCIENCE INSTITUTE OF SINGAPORE MEDICINE let 7a LIN28B protein microRNA stem cell factor unclassified drug LIN28B protein, human microRNA mirnlet7 microRNA, human RNA binding protein small interfering RNA acute myeloid leukemia animal experiment animal model animal tissue Article bioinformatics cancer inhibition carcinogenicity cell cycle arrest cell metabolism cell proliferation colony formation controlled study female G2 phase cell cycle checkpoint gene gene function gene overexpression gene silencing gene targeting genetic association hematopoiesis human human cell IGF2BP1 gene in vivo study KDM4A gene leukemia cell leukemogenesis LIN28B gene microarray analysis mouse nonhuman oncogene PSAT1 gene signal transduction tumor xenograft acute myeloid leukemia animal cell cycle checkpoint cell proliferation gene expression regulation genetics metabolism nonobese diabetic mouse pathology RNA interference SCID mouse tumor cell line Animals Cell Cycle Checkpoints Cell Line, Tumor Cell Proliferation Female Gene Expression Regulation, Leukemic Humans Leukemia, Myeloid, Acute Mice Mice, Inbred NOD Mice, SCID MicroRNAs RNA Interference RNA, Small Interfering RNA-Binding Proteins 10.1186/s13045-017-0507-y Journal of Hematology and Oncology 10 1 138 2020-09-01T00:53:26Z 2020-09-01T00:53:26Z 2017 Article Zhou, J, Bi, C, Ching, Y.Q, Chooi, J.-Y, Lu, X, Quah, J.Y, Toh, S.H.-M, Chan, Z.-L, Tan, T.Z, Chong, P.S, Chng, W.-J (2017). Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia. Journal of Hematology and Oncology 10 (1) : 138. ScholarBank@NUS Repository. https://doi.org/10.1186/s13045-017-0507-y 17568722 https://scholarbank.nus.edu.sg/handle/10635/173782 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	let 7a LIN28B protein microRNA stem cell factor unclassified drug LIN28B protein, human microRNA mirnlet7 microRNA, human RNA binding protein small interfering RNA acute myeloid leukemia animal experiment animal model animal tissue Article bioinformatics cancer inhibition carcinogenicity cell cycle arrest cell metabolism cell proliferation colony formation controlled study female G2 phase cell cycle checkpoint gene gene function gene overexpression gene silencing gene targeting genetic association hematopoiesis human human cell IGF2BP1 gene in vivo study KDM4A gene leukemia cell leukemogenesis LIN28B gene microarray analysis mouse nonhuman oncogene PSAT1 gene signal transduction tumor xenograft acute myeloid leukemia animal cell cycle checkpoint cell proliferation gene expression regulation genetics metabolism nonobese diabetic mouse pathology RNA interference SCID mouse tumor cell line Animals Cell Cycle Checkpoints Cell Line, Tumor Cell Proliferation Female Gene Expression Regulation, Leukemic Humans Leukemia, Myeloid, Acute Mice Mice, Inbred NOD Mice, SCID MicroRNAs RNA Interference RNA, Small Interfering RNA-Binding Proteins
spellingShingle	let 7a LIN28B protein microRNA stem cell factor unclassified drug LIN28B protein, human microRNA mirnlet7 microRNA, human RNA binding protein small interfering RNA acute myeloid leukemia animal experiment animal model animal tissue Article bioinformatics cancer inhibition carcinogenicity cell cycle arrest cell metabolism cell proliferation colony formation controlled study female G2 phase cell cycle checkpoint gene gene function gene overexpression gene silencing gene targeting genetic association hematopoiesis human human cell IGF2BP1 gene in vivo study KDM4A gene leukemia cell leukemogenesis LIN28B gene microarray analysis mouse nonhuman oncogene PSAT1 gene signal transduction tumor xenograft acute myeloid leukemia animal cell cycle checkpoint cell proliferation gene expression regulation genetics metabolism nonobese diabetic mouse pathology RNA interference SCID mouse tumor cell line Animals Cell Cycle Checkpoints Cell Line, Tumor Cell Proliferation Female Gene Expression Regulation, Leukemic Humans Leukemia, Myeloid, Acute Mice Mice, Inbred NOD Mice, SCID MicroRNAs RNA Interference RNA, Small Interfering RNA-Binding Proteins Zhou, J Bi, C Ching, Y.Q Chooi, J.-Y Lu, X Quah, J.Y Toh, S.H.-M Chan, Z.-L Tan, T.Z Chong, P.S Chng, W.-J Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
description	10.1186/s13045-017-0507-y
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Zhou, J Bi, C Ching, Y.Q Chooi, J.-Y Lu, X Quah, J.Y Toh, S.H.-M Chan, Z.-L Tan, T.Z Chong, P.S Chng, W.-J
format	Article
author	Zhou, J Bi, C Ching, Y.Q Chooi, J.-Y Lu, X Quah, J.Y Toh, S.H.-M Chan, Z.-L Tan, T.Z Chong, P.S Chng, W.-J
author_sort	Zhou, J
title	Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
title_short	Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
title_full	Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
title_fullStr	Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
title_full_unstemmed	Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia
title_sort	inhibition of lin28b impairs leukemia cell growth and metabolism in acute myeloid leukemia
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/173782
_version_	1800914190532083712

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

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