Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor

Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor

10.1038/s41598-018-30686-1

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Bibliographic Details
Main Authors:	Subhash, V.V, Yeo, M.S, Wang, L, Tan, S.H, Wong, F.Y, Thuya, W.L, Tan, W.L, Peethala, P.C, Soe, M.Y, Tan, D.S.P, Padmanabhan, N, Baloglu, E, Shacham, S, Tan, P, Koeffler, H.P, Yong, W.P
Other Authors:	PHARMACY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	antineoplastic agent hydrazine derivative protein p53 selinexor triazole derivative adult animal apoptosis cell cycle cell nucleus cell proliferation drug effect drug screening female human male metabolism mouse nucleocytoplasmic transport pathology stomach tumor tumor cell line Active Transport, Cell Nucleus Adult Animals Antineoplastic Agents Apoptosis Cell Cycle Cell Line, Tumor Cell Nucleus Cell Proliferation Female Humans Hydrazines Male Mice Stomach Neoplasms Triazoles Tumor Suppressor Protein p53 Xenograft Model Antitumor Assays
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174208
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Institution:	National University of Singapore

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