KIF1B? increases ROS to mediate apoptosis and reinforces its protein expression through O2 - In a positive feedback mechanism in neuroblastoma

• Main Authors: Angelina, C, Tan, I.S.Y, Choo, Z, Lee, O.Z.J, Pervaiz, S, Chen, Z.X
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2020
• Subjects: cation; diphenyliodonium salt; gliotoxin; KIF1B protein, human; kinesin; reactive oxygen metabolite; small interfering RNA; superoxide; antagonists and inhibitors; apoptosis; chemistry; drug effect; genetics; human; metabolism; neuroblastoma; pathology; protein synthesis; RNA interference; tumor cell line; upregulation; Apoptosis; Cell Line, Tumor; Gliotoxin; Humans; Kinesin; Neuroblastoma; Onium Compounds; Protein Biosynthesis; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Superoxides; Up-Regulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175088
• Institution: National University of Singapore

10.1038/s41598-017-17192-6