YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2

YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2

10.1186/s12974-017-0866-x

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Li, Z.-Y, Chung, Y.H, Shin, E.-J, Dang, D.-K, Jeong, J.H, Ko, S.K, Nah, S.-Y, Baik, T.G, Jhoo, J.H, Ong, W.-Y, Nabeshima, T, Kim, H.-C
مؤلفون آخرون:	ANATOMY
التنسيق:	مقال
منشور في:	2020
الموضوعات:	1 alkyl 2 acetylglycerophosphocholine esterase 1 alkyl 2 acetylglycerophosphocholine esterase 1 amyloid beta protein[1-42] amyloid precursor protein bilobalide cyclooxygenase 2 Ginkgo biloba extract ginkgolide A ginkgolide B ginkgolide C isorhamnetin kaempferol meloxicam presenilin 1 quercetin reactive oxygen metabolite terpene thrombocyte activating factor receptor unclassified drug yy 1224 amyloid beta protein amyloid beta-protein (1-42) lactone peptide fragment plant extract trilactone animal cell animal experiment animal model animal tissue antiinflammatory activity antioxidant activity Article controlled study COX 2 gene down regulation enzyme inhibition gene expression regulation knockout mouse learning disorder memory disorder microglia mouse nerve cell stimulation neuroprotection neurotropism nonhuman PAF acetylhydrolase 1 gene pilot study platelet activating factor receptor gene protein expression protein localization retreatment transgenic mouse upregulation Alzheimer disease animal antagonists and inhibitors biosynthesis degenerative disease gene expression genetics Ginkgo biloba isolation and purification metabolism Alzheimer Disease Amyloid beta-Peptides Amyloid beta-Protein Precursor Animals Cyclooxygenase 2 Gene Expression Lactones Mice Mice, Knockout Mice, Transgenic Neurodegenerative Diseases Peptide Fragments Plant Extracts Presenilin-1 Reactive Oxygen Species Terpenes
الوصول للمادة أونلاين:	https://scholarbank.nus.edu.sg/handle/10635/179510
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
المؤسسة:	National University of Singapore

الانترنت

https://scholarbank.nus.edu.sg/handle/10635/179510