Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays

• Main Authors: Xiong Tan, B, Brown, C.J, Ferrer, F.J, Yuen, T.Y, Quah, S.T, Chan, B.H, Jansson, A.E, Teo, H.L, Nordlund, P, Lane, D.P
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: MDM2 protein, human; MDM4 protein, human; nuclear protein; oncoprotein; peptide; protein binding; protein MDM2; protein p53; bioassay; HCT 116 cell line; human; metabolism; physiology; procedures; tumor cell line; Biological Assay; Cell Line, Tumor; HCT116 Cells; Humans; Nuclear Proteins; Peptides; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180326
• Institution: National University of Singapore

10.1038/srep12116